(factors are you size, weight, kidney function, metabolic rate and so on) That means 50% after first half life, 25% after second, 12.5 after third, 6.25 after fourth down to less than 2% after six. Posted January 22, 2016 by Michael Batnick “Time in the market, not timing the market” is the rallying cry for buy and hold investors. If you'd prefer, feel free to email me. Also don't hesitate to call the nurses and ask them if there is anything else you can do to help her to better tolerate these treatments. Insomnia also made frequent visits during my chemo. (I have a new tagline for Taxotere: “Taxotere, putting the tax on your liver since 1996.”) When you are getting chemo, your liver can have an indirect effect on keeping your white blood cells, monocytes and neutrophils at a healthy level. The content on this site is for informational purposes only. I did find that some of the other side effects actually were better with successive treatments instead of getting worse (GI issues and mouth taste/texture). So my sense of TASTE is returning... must be almost time for another dose... LOL. In some ways was easier, in others was more taxing (pun intended)! Your resistance to infection is usually at its lowest point around 7–14 days after the docetaxel has been given. She is also tired of taking pills. I would definitely talk to Donna's doctor about the sleep issue. posted by Mardi. I receive oral and IV dexamethasone (Decadron) instead of Prednisone with IV taxotere, every three weeks. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. By Monday I was OK to go back to work, just a little tired. I know the S/E's kick in from the 3rd/4th day so am making the most of feeling great while it lasts - even got people coming for a meal tonight, hope I dont flag halfway thru ! I did not get any worse for the remaining treatments. Between the first and second treatment I bounced back pretty well, but between the 3rd and 4th it took longer. I haven't had a CRASH, but I've had a couple of days of SAGGING energy. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. And yes, for me at least, it is cumulative and is a bit worse each cycle. Most don't understand the battle is not only physical, but mental, emotional, and spiritual. I finished my initial session of chemo with four treatments of Taxotere. Many husbands end up feeling so helpless and drained that they give up and don't know what else to do. They weren't truly cube shaped, but the more tub-bottom shapes. Like Donna, I too have a really good hubby, he took the reins of household chores together with my 17yr old daughter. @Steve55777 Re:diet what do you eat that is not vegan? Rough night last night; not sleeping well. Taxotere has been known to cause burning, tingling or numbness in your appendages due to nerve damage. I was on Taxotere and Cytoxan...day 3 and 4 were the worst for me. Even if a patient feels that his chemotherapy is causing more grief than relief, it can be discontinued; there […] Hopefully, you might escape the crash but incase you don't, do make sure to take ISU-Cyclone's advice and if interested, see my diary of my chemo treatment here: Your body will tolerate that first dose without too much trouble..But as time goes on and the treatments start to add up, the effect will become more pronounced..I take a couple of Dexamethasone the day before, the day of and the day after the infusion to suppress any allergic reaction. When I was going through my cancer treatment one of the doctors in the treatment facility told me no two patients they were currently treating (100’s) were on the same drug regimen, and no two patients had the same reaction to any of the drugs. Small meals every 2-3 hrs worked the best for me. Hematologic toxicity is increased at higher doses and in patients with elevated baseline liver function tests. Please tell her to take it easy and rest up a few days before her chemo and to plan on alot of down time for few days after the 2nd day after chemo. Lost only 3,4 pounds (do in part to the summer temps), generally felt ok. They can be debilitating. Treatments started on Oct 2, 2014 and then every 21 days from there with the exception of late Dec. which was 25 days because the 21st day fell on Christmas day. Other side effects included sore throat and cough, sharp stomach and esophageal pain, swollen and painful tongue. However I do admit I did over the course of 4 AC treatments (3 weeks apart) felt almost depressed in the sense that I had little motivation to do anything, even getting out of bed, taking a shower, eating although I was hungary and going out in public became increasingly difficult for me. Since its initial approval by the U.S. Food and Drug Administration in 1996, it has gained additional approvals for treating cancers of the head, neck, stomach, and prostate, as well as non-small cell lung cancer. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. This involves wearing a cold cap before, during and for one to two hours after your treatment with the chemotherapy drugs. During administration I received decadron, benadryl and zofran. Copyright 2000-2019 © Cancer Survivors Network, Ask for some ativan so she can sleep also, Hubby and Donna .. It is also a blessing that you are reaching out to find information from others going through the same thing so that you can help your wife. Take care. I went back to work on Tuesday, but wasn't feeling the greatest. Fatal reactions have occurred in patients despite premedication, and all patients should be pretreated with corticosteroids, … I did not start feeling better until the 5 or 6th day after chemo. It effects a person on every level possible. How many treatments is she having? She is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). I was really good at that! WBC is a little low, so I will get NEULASTA... other test results aren't in yet. They did have "ice cubes", so I chewed those. I just had another C-11 Acetate scan yesterday in Phoenix which confirmed the Lupron/Casodex/Taxotere regimen has worked for me. Individual experiences and side effects differ widely from one man to another. Chemotherapy with Taxotere (docetaxel) might not be considered because the side effects are misunderstood. for me it was the week after the infusion.....I just fall apart....tired, ache, intestinal issues...etc. So pretty much gone water or no after four days. I had no sleepless issues on A/C but on Taxol I did - first meds given me by my Chemo Dr did not help only gave horrible nightmares (which I don't normally have) but my PA switched me to the lowest does of another med and it worked great. A few days after infusion, my normal temperature of 97 went to 99. Her body is going through so much right now. HI, My first does of chemo was not so bad. 23 days: 10/7/2009: 1: stage II breast cancer: During treatments, body aches, chemo brain, neuropathy, chemically induced menopause were the worst ones. i had my first AC on June 10 (a Thursday), and the worst days for me were Sunday and Monday. Taxotere is classified as a cytotoxic drug, which is a drug that stops rapidly dividing cells. I felt sicker than a dog but it only lasted for 15 minutes and then it passed. It is best to read this information with our general information about chemotherapy and the type of cancer you have.. Last reply: 6 years ago I got off lightly on the 4 AC, only had a couple of very bad days each cycle. Intravenous route (Solution) Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. Between blood pressure (3 a day), xanex (she's only taking at night), two kinds of anti-nausea drugs, claratin (supposed to help with bone pain after shot), a softener, and acidophilus. we are all individuals with our own health issues, and the way we react to a drug, or pain, or anything is unique to us. My bad days seemed to be the 3rd to 5th day after treatment .. and these days increased as my chemo treatments wore on. Wishing you continued success with no crashes. On the eve of Oct 21 his temperature got to 101.3F in the evening so we went to the ER and they kept him in the hospital until they got his fever down and his white blood cells up. This time they dropped my doses by 20% for both the Taxotere and Carboplatin. As for the Neulasta, I began with that day after #1, but when fevers settled in, my doc thought it might be from Neulasta, so I went to daily Neupogen shots following Taxotere #2-6. I had AC on Wed by that night I was having stomach issues. Next time I will. I'll be vigilant, and hydrated... My crash comes in the third to fifth day after, and is unpredictable. As women especially moms it is really hard for us to let go and accept that our bodies will now have its limits. Chemo brain takes the proper terminology from me. Lots of fatigue, sometimes diarrhea, sometimes a fever. i think we all wish you and your wife nothing but good, and we can offer hope that you will make it through this, because you will get through this ; ), Susan is right everyone is different. I have 2 weeks down and Infusion #2 is 1 week away... We'll do blood work Monday, n infusion Tuesday. Premedication with a corticosteroid pill starting a day prior to Taxotere infusion for 3 days is given to reduce the severity of fluid retention and allergic reactions. She keeps telling me that she is not strong enough to do this; and I tell her that she is stronger than she thinks she is. One of the chemo nurses (the nice one) did call her yesterday and say if she wasn't feeling better today to come in and they could give her some fluids, but I think she is gonna make it through without it. Charts like the one below show the damage an investor would have done if they missed out on just the best 25 days (out of 11,620) since 1970. I endured chemotherapy. Taxotere’s Effect on Your Body. The 3rd week I just start to feel normal....and then whoops, time for another infusion to start the cycle. Last night about 9:00 the fog started lifting. You gals going through it try it and let me know. I think the hard part is going to be coming out for round two. TC is used to treat breast cancer.It may sometimes be used to treat other cancers. Tell Donna, it will get better, food will taste good again, but in order to keep her strenght up she must eat even if she is not hungry or just taste awful. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. It was lovely to have my parents around for a couple of days, just to help look after me and my husband, and keep me company when he went off to work. while I was on AC. Good luck and take good care of her. After the week was up, I was almost my old self again. I have been a bit achey on Sunday with that nueropathy stuff in my legs and feet but other that that I am doing GREAT!!!!!!!! Last night she was saying that she doesn't know how she is going to get through the next treatment, especially since they supposedly get worse each time. I am on Taxotere and Cytoxin which I get every three weeks. That was on the dose dense A/C. No history of cancer in my family -- it's been waiting patiently for me! (the 2%) And did you crash change your diet? Yes....she is having a much more aggressive treatment plan than I did so I hope some other ladies here that have had that coctail and frequency will be able to give you more advice. January 8, 2016 katejig bald , breast cancer , Cancer , chemo , chemotherapy , cytoxan , hair loss , sickness , taxotere 2 Comments It controlled the nausea together with the meds. However she feels the 1st time is usually how she will feel for the remainder of that drug. Is day 4 the worst day? xoxoxoxo Lynn. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. Days 1 & 7, I was tired but could function to some degree - I made it to infusions. I wish you two the very best. Make sure she is getting alot of water, eat fruits and vegetables. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Many minor ones: loss of taste, all day tearing and runny nose, hair loss. We needed to make a spread sheet of what pills to take and when. In clinical trials, the median time to nadir was 7 days, and the median duration of severe neutropenia (less than 500 cells/mm3) was 7 days. My onocologist prefers it to Taxol. Once the steroids wear off, usually by the 3rd day, you will see her get very fatigued and want to lay around the house most of the day. Chemo consisted of 6 total treatments - 1 treatment every 21 days of a variety of steroids, anti-nausia meds and anti allergy meds along with 300mg of Taxal & 580mg of Carboplatin. That was EVERY week as opposed to every 2 weeks on A/C. After first AC on Wed. and doing "okay" Thurs. By Christina Morales | Apr 20, 2018. The pain was scored accordingly to a 1 to 10 scale of intensity. Taxol/Taxotere and Cytoxan (TC) therapy is one of the most common types of chemotherapy given to women with early-stage breast cancer. I was on Taxotere and Cytoxan...day 3 and 4 were the worst for me. The onset of all my side effects were predictable after the first round of AC. n Generally, chemotherapy is not as toxic as we think. I did not get any worse for the remaining treatments. Organ and structural triggers of the urinary bladder such as Painful Bladder result in painful spasmodic contractions of the pelvic floor muscles and ligaments that mimic I have seen patients varying in age from teens to … If you have been diagnosed with breast cancer and are undergoing Taxotere (docetaxel) chemotherapy treatments, you are all too familiar with bad days. Are you getting 4 or 6 Taxotere treatments? Michele. Great news on not getting a chemo crash. The bone pains are not nice at all, they've been bad enough to seriously affect my sleep, but even so, once again I get the impression I got off quite lightly this time. Taxotere is used to treat breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer as well as metastatic prostate cancer. Then, at the end of the cycle, the chemo schedule repeats to start the next cycle. My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. Lorrie. The next drug will effect her differently. Days 4 and 5 were the absolute worst - but to be honest, I didn't really take much in terms of painkillers. I do know that everyone is different, but I just wanted some sort of idea what everyone elses bad days were. I also went in every 2 weeks for 5 months. Lorrie, You may want to ask the onc to prescribe her some ativan to take at night. I have finished 4 cycles so far with 4 more to go. Hi... Today was infusion #2 day... it went great, although there were no ice chips. I went to Moes, and got a Chicken Bowl (double beans, no rice, 1st meat in about, /www.healingwell.com/community/default.aspx?f=35&m=3987553&g=4010036#m4010036. Thanks guys!! every Tuesday for 18 weeks straight .. Of those who experienced pain during the seven days after treatment, the average rating for pain at its worst was 5.15 for muscle pain and 5.02 for joint pain. I thought I was crashing on day 2, but it was really the diet I'm following. I wasn't happy about. The major dose-limiting toxicity of this drug is reversible marrow suppression. I started taking a iron supplement to support RBC..WBC is still okay. My chemo cocktail was different than Donna's, but I did have infusions on Wednesdays (Cytoxan and Taxotere every 3 weeks - 4 treatments) with a Neulasta shot on Thursdays. The chemo does tend to keep you from sleeping sometimes even though you are very tired. I am praying for her and hope she will be up and around with new strength soon. As you know from Carbo/Alimta, the effects of chemo can be cumulative so it's super important to stay hydrated, well nourished and exercise if you can. Weekly taxol : which days will be worst Breast cancer. If she knows that, then she could adjust her life that way for a while. Use of this online service is subject to the disclaimer and the terms and conditions. I was on taxotere and id have my treatments on monday, and wednesday & thursdays were my bad days. Well if I score this like a boxing match, so far I'm giving round one to Donna. As others have said, everyone is different. I thought I missed the bullet for several days after my first infusion too, but eventually, it was time to pay the piper. Sleepless nights, yeah, very common and hard when you have to still get up to go to work. But nothing ever happened and it passed as soon as it happened. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. One well-known, common side effect of Reversible marrow suppression was the major dose-limiting toxicity of TAXOTERE [see WARNINGS AND PRECAUTIONS].The median time to nadir was 7 days, while the median duration of severe neutropenia (<500 cells/mm 3) was 7 days.Among 2045 patients with solid tumors and normal baseline LFTs, severe neutropenia occurred in 75.4% and lasted for more than 7 days … I'd also consider doing Wednesday infusions to put your worst days on the weekends (unless you work weekends). It's important to take things day by day. Though I've been done with chemo med taxotere and carbon back in April, Im still on Herceptin for another 4months,my bad days are less and my better days are longer. The prospect of 12 weekly taxol is a bit daunting. Days 3/4 to today, painful bones. Good luck to her. Neulasta shot .. threw me for a loop ... my acky body. With others, it is given for a few days in a row, or once a week. I had my first chemo treatment this past Wednesday also and I have been doing fine all along except for Friday. My first infusion did not include Neulasta. Lorrie. and Friday, Donna did too much on Saturday, taking my daughter to the mall; shopping for most of the day. Worst Days On Taxotere Cramps Remedies Exercise some also deal with anxiety in the years leading up to full-blown menopause a time called perimenopause. I keep thinking if I had made sure to eat something every hour maybe it wouldn't have been so bad. For me the fatigue was a bit cumulative. For example, with some drugs, the chemo is given only on the first day of the cycle. Your doctor will prescribe the exact regimen. Good luck with round two NOTkidneystones! That seems to help me. For example, when I received the FEC chemo I did have to get injections for five days (on days 8 to 12 after every cycle) to promote white cell formation (Filgrastim). Hang in there. It Was The Best of Days, It Was The Worst of Days. 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And zofran third to fifth day after worst days on taxotere.. and these days as! Sleeping sometimes even though you are very tired and esophageal pain, swollen and painful tongue round of AC it...

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